Dental experts discover biological imbalance is the link between gum and kidney disease

An imbalance of the body’s oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found. Periodontitis—or gum disease—is a common, inflammatory disease which causes bleeding gums, wobbly or drifting teeth and can […]

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New clues why gold standard treatment for bipolar disorder doesn’t work for majority of patients

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don’t respond to it. This leaves them at risk for debilitating, potentially life-threatening mood swings. Researchers at the Salk Institute have found that the culprit may lie in gene activity—or lack of it. A new study […]

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Researchers uncover a potential treatment for an aggressive form of lung cancer

Researchers at the Children’s Medical Center Research Institute at UT Southwestern (CRI) have discovered a new metabolic vulnerability in a highly aggressive form of non-small cell lung cancer (NSCLC). These findings could pave the way for new treatments for patients with mutations in two key genes—KRAS and LKB1. Patients whose tumors contain both of these […]

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Ibrutinib with rituximab in previously untreated CLL: Indication of added benefit over FCR

The combination of ibrutinib plus rituximab is approved for the treatment of adults with previously untreated chronic lymphocytic leukemia (CLL). In an early benefit assessment, the German Institute for Quality and Efficiency in Health Care (IQWiG) now examined which advantages and disadvantages this drug combination has for the patients. For patients who could also be […]

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New clues to prostate cancer: Why aggressive subtype can resist treatment

Australian research has identified a new mechanism in which prostate cancer cells can ‘switch’ character and become resistant to therapy. These findings, just published in Cell Reports, are an important development in unraveling how an aggressive subtype of prostate cancer, neuroendocrine prostate cancer (NEPC), develops after hormonal therapies. It is well established that some tumors […]

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